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Fungi
Aspergillus sp.
Disease
Aspergillosis
Symptoms

Symptoms of allergic bronchopulmonary aspergillosis may include:

  • Cough, Coughing up blood or brownish mucus plugs, Fever
  • General ill feeling (malaise), Wheezing, Weight loss

Other symptoms depend on the part of the body affected, and may include:

  • Blood in the urine, Bone pain, Chest pain, Chills, Decreased urine output
  • Headaches, Increased phlegm production, which may be bloody
  • Shortness of breath
  • Skin sores (lesions)
  • Vision problems
Treatment

A fungus ball is usually not treated (with antifungal medicines) unless there is bleeding into the lung tissue. In that case, surgery is needed.

Invasive aspergillosis is treated with several weeks of an antifungal drug called voriconazole. It can be given by mouth or directly into a vein (IV). Amphotericin B, echinocandins, or itraconazole can also be used.

Endocarditis caused by Aspergillus is treated by surgically removing the infected heart valves. Long-term antifungal therapy is also needed.

Antifungal drugs alone do not help people with allergic aspergillosis. Allergic aspergillosis is treated with drugs that suppress the immune system (immunosuppressive drugs) -- most often prednisone taken by mouth.

Preventive measures

Be careful when using medications that suppress the immune system. Preventing AIDS also prevents certain diseases, including aspergillosis, that are associated with a damaged or weakened immune system.

 
     
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